Normalization of retinal nerve fiber layer thickness measurements made by time domain-optical coherence tomography
US8911089B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 19, 2010 |
| Grant date | Dec 16, 2014 |
| Priority date | — |
| Expiry date | Dec 12, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01B2290/65
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A scan location matching (SLM) method identifies conventional time domain optical coherence tomography (TD-OCT) circle scan locations within three-dimensional spectral domain OCT scan volumes. A technique uses both the SLM algorithm and a mathematical retinal nerve fiber bundle distribution (RNFBD) model, which is a simplified version of the anatomical retinal axon bundle distribution pattern, to normalize TD-OCT thickness measurements for the retinal nerve fiber layer (RNFL) of an off-centered TD-OCT circle scan to a virtual location, centered on the optic nerve head. The RNFBD model eliminates scan-to-scan RNFL thickness measurement variation caused by manual placement of TD-OCT circle scan.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.