Patent · US Active

Method for the determination of the DNA methylation level of a CPG position in identical cells within a tissue sample

US8912129B2 · kind B2 · utility

2Cited by

0References

17Claims

0Family size

Assignee

EPIGENOMICS AG · DE

Inventors

Joern Lewin · Berlin, DE
Kurt Berlin · Stahnsdorf, DE

Key dates

Filing date	Nov 17, 2006
Grant date	Dec 16, 2014
Priority date	—
Expiry date	Sep 21, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6827
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Aspects of the present invention relate to the determination of the DNA methylation level at one or more CpG position within cells of a defined type in a tissue sample. This methylation level is deduced from the total DNA methylation level of all cells of the sample and from the content of said cells of interest. In aspects of the invention, the cell content is determined by means of histopatholoy, staining methods, antibodies, expression analysis or DNA methylation analysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.