Hydrophilic/hydrophobic polymer networks based on poly(caprolactone fumarate), poly(ethylene glycol fumarate), and copolymers thereof
US8912247B2 · kind B2 · utility
2Cited by
41References
8Claims
0Family size
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Key dates
| Filing date | Apr 28, 2006 |
| Grant date | Dec 16, 2014 |
| Priority date | — |
| Expiry date | Jul 14, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G63/83
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Improved methods for preparing polyethylene glycol fumarate) are disclosed. Methods for chemically crosslinking or photocross-linking hydrophilic polyethylene glycol fumarate) with hydrophobic polymers such as poly(propylene fumarate) (PPF) and poly(caprolactone fumarate) (PCLF) to form various hydrogels (FIG. 1) with controllable hydrophilicity are also disclosed. The hydrogels are useful in the fabrication of injectable and in-situ hardening scaffolds for application in skeletal reconstruction. An injectable material including the hydrogels may be useful in controlled drug release.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.