Patent · US Active

Adsorbents for the adsorption of hepcidin

US8915875B2 · kind B2 · utility

2Cited by

3References

6Claims

0Family size

Assignee

Fresenius Medical Care Deutschland GmbH · DE

Inventors

Jutta Passlick-Deetjen · Gießen, DE
Wolfgang Hofmann · Heroldsbach, DE

Key dates

Filing date	Jul 15, 2010
Grant date	Dec 23, 2014
Priority date	—
Expiry date	Dec 16, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2982
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to a device and a method for depletion of hepcidin from blood for treatment of iron deficiency, in particular in anemic patients suffering from chronic renal failure, with the goal of increasing the availability of iron in the body and thus improving the treatment of the anemia. The hepcidin adsorbent comprises a matrix and a hepcidin-binding ligand covalently bonded to the matrix with an affinity having a dissociation constant KD of less than 200 nM.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.