Arrangement and method using microsensors for measuring cell vitalities

US8916035B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM VETMEDICA GMBH · DE

Inventors

• Alexander Frey · Munich, DE
• Walter Gumbrecht · Herzogenaurach, DE
• Peter Paulicka · Erlangen, DE
• Meinrad Schienle · Ottobrunn, DE
• Daniel Sickert · Nuremberg, DE
• Manfred Stanzel · Erlangen, DE

Key dates

• Filing date: Sep 29, 2010
• Grant date: Dec 23, 2014
• Expiry date: Nov 13, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/48735
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

An arrangement and a method measures cell vitalities with a sensor array. The sensor array is formed on a surface of a semiconductor chip. The semiconductor chip has integrated circuits and an integrated circuit is associated with each sensor of the sensor array, for processing the measurement signals of the respective sensor. The integrated circuits are formed in the semiconductor chip spatially in each case below the associated sensor and neighboring sensors of the sensor array have a center-to-center in the range of micrometers. The pH and/or pO2 can be measured in the environment of a living cell.