SPARC and methods of use thereof
US8916204B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Mar 13, 2013 |
| Grant date | Dec 23, 2014 |
| Priority date | — |
| Expiry date | Mar 13, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying the SPARC protein or RNA in a sample isolated from the mammal. The invention further provides kit for predicting the response of a mammalian tumor to a chemotherapeutic agent, comprising a means for the isolation of protein or RNA from the tumor, a SPARC protein or RNA detection and quantification means, control RNAs, and rules for predicting the response of the tumor based on the level of SPARC protein or RNA in tumor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.