Patent · US Active

Pharmacokinetically improved compounds

US8916576B2 · kind B2 · utility

6Cited by
2References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 14, 2012
Grant dateDec 23, 2014
Priority date
Expiry dateDec 14, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.