Tricyclic derivatives, process for their preparation and their use as kinase inhibitors
US8916577B2 · kind B2 · utility
2Cited by
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21Claims
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Assignee
Inventors
Key dates
| Filing date | Jan 19, 2012 |
| Grant date | Dec 23, 2014 |
| Priority date | — |
| Expiry date | Jan 19, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New substituted tricyclic compounds of formula (I) are described, wherein R1, R2, X, Y, Z are herein defined, having protein kinase inhibiting activity. The invention includes methods to prepare the compounds of formula (I), pharmaceutical compositions containing them, and their use in therapy, in particular for the treatment of diseases caused by and/or associated with dysregulated activity of protein kinase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.