Method of breath analysis for determining liver capacity or microcirculation using 13C-labeled methacetin substrate
US8920334B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 26, 2006 |
| Grant date | Dec 30, 2014 |
| Priority date | — |
| Expiry date | May 1, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to an analysis method for determining a functional parameter of an organ of a human or animal individual by measuring the 13CO2 content in the air exhaled by the individual to which a substrate has been administered the reaction of which in the body of the individual enriches the air exhaled by the individual with 13CO2. The method is characterized by using a measuring device, the maximum reaction rate of the substrate in the body of the individual being determined via a change of the measured 13CO2 content in the air exhaled by the individual using zero-order enzyme kinetics. The invention also relates to an aqueous methacetin solution for use in said analysis method, the pH of the solution being greater 7.0. The invention also relates to a face mask (1) for use in the inventive method for separating the exhaled air from the air inhaled by an individual. Said face mask comprises a face mask body (2) and an air cushion (3) encircling the face mask body. Said air cushion is filled with a gas and establishes a substantially gas-tight contact between the face of the individual and the face mask (1) placed on the face of the individual so that the air required by …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.