Medical devices having a coating of inorganic material

US8920491B2 · kind B2 · utility

Assignee

• Boston Scientific Scimed, Inc. · US

Inventors

• Aiden Flanagan · Kilcolgan, IE
• John Kilcooley · Gort, IE
• Tim O'Connor · Galway, IE
• Barry James O'Brien · Galway, IE
• Dominique Seidel · Munich, DE
• Michael Kuehling · Munich, DE
• Torsten Scheuermann · Munich, DE
• Jan Weber · Maple Grove, US

Key dates

• Filing date: Apr 17, 2009
• Grant date: Dec 30, 2014
• Expiry date: Sep 13, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2300/61
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of for…