Loading technique for preparing radionuclide containing nanoparticles
US8920775B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 16, 2010 |
| Grant date | Dec 30, 2014 |
| Priority date | — |
| Expiry date | Dec 21, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/127
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel composition and method for loading delivery systems such as liposome compositions with radionuclides useful in targeted diagnostic and/or therapy of target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The composition and methods of the invention find particular use in diagnosing and imaging cancerous tissue and, in general, pathological conditions associated with leaky blood vessels in a subject. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique. One specific aspect of the invention is directed to a method of producing nanoparticles with desired targeting properties for diagnostic and/or radio-therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.