Patent · US Active

Compositions and methods for the detection diagnosis and therapy of hematological malignancies

US8920776B2 · kind B2 · utility

45Cited by
2References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 22, 2003
Grant dateDec 30, 2014
Priority date
Expiry dateAug 25, 2028

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/158
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are methods and compositions for the detection, diagnosis, prognosis, and therapy of hematological malignancies, and in particular, B cell leukemias, lymphomas and multiple myelomas. Disclosed are compositions, methods and kits for eliciting immune and T cell responses to specific malignancy-related antigenic polypeptides and antigenic polypeptide fragments thereof in an animal. Also disclosed are compositions and methods for use in the identification of cells and biological samples containing one or more hematological malignancy-related compositions, and methods for the detection and diagnosis of such diseases and affected cell types. Also disclosed are diagnostic and therapeutic kits, as well as methods for the diagnosis, therapy and/or prevention of variety of leukemias and lymphomas.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.