Androgen receptor modulating carboxamides
US8921378B2 · kind B2 · utility
13Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 20, 2012 |
| Grant date | Dec 30, 2014 |
| Priority date | — |
| Expiry date | Apr 20, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I) or (II)wherein Rx, Rz, R9, R10, R14, R14′, R15, R15′, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.