N-cyclopropyl-N-piperidinyl-amide derivatives, pharmaceutical compositions and uses thereof

US8921398B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Armin Heckel · Biberach an der Riß, DE
• Frank Himmelsbach · Mittelbiberach, DE
• Elke Langkopf · Biberach an der Riß, DE
• Bernd Nosse · Biberach an der Riß, DE
• Neil Ashweek · San Diego, US
• Nicole Harriott · San Diego, US

Key dates

• Filing date: Jun 6, 2012
• Grant date: Dec 30, 2014
• Expiry date: May 10, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of general formula I,wherein R1, LP, HetAr, Ar, and n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.