Patent · US Active

Therapeutic isoxazole compounds

US8921399B2 · kind B2 · utility

1Cited by
15References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 16, 2012
Grant dateDec 30, 2014
Priority date
Expiry dateApr 16, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides a compound of formula I:wherein A1, A2, A3, R1, X, Y, and B have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of monoamine oxidase B (MAO-B) enzyme function and are useful for improving cognitive function and for treating psychiatric disorders in animals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.