Compounds

US8921405B2 · kind B2 · utility

Assignee

• OREXO AB · SE

Inventors

• Roland Pfau · Biberach, DE
• Kirsten Arndt · Biberach, DE
• Henri Doods · Warthausen, DE
• Klaus Klinder · Oggelshausen, DE
• Raimund Kuelzer · Mittelbiberach, DE
• Dimitrijs Lubriks · Rīga, LV
• Juergen Mack · Biberach an der Riß, DE
• Benjamin Pelcman · Stockholm, SE
• Henning Priepke · Warthausen, DE
• Robert Roenn · Uppsala, SE
• Dirk Stenkamp · Biberach, DE
• Edgars Suna · Rīga, LV

Key dates

• Filing date: Jul 15, 2013
• Grant date: Dec 30, 2014
• Expiry date: Jul 15, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of general formula Iin which A, L, M, Q2, Q3, Q4, R1, R5, Ra, Rb, Rc, W, X, Y, Z1, Z2, Z3 are defined in the description, the salts thereof, particularly the physiologically acceptable salts thereof. The compounds are of potential utility in the treatment and/or prevention of inflammatory diseases and associated conditions, in particular, in the treatment and/or prevention of pain. The invention also relates to the use of such compounds as medicaments, to pharmaceutical compositions containing them, and to their preparation.