Rationally improved isoniazid and ethionamide derivatives and activity through selective isotopic substitution
US8921569B2 · kind B2 · utility
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Key dates
| Filing date | Feb 6, 2013 |
| Grant date | Dec 30, 2014 |
| Priority date | — |
| Expiry date | Feb 6, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/86
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of isotopically labeled derivatives of isoniazid, ethionamide and related compounds as effective therapy for the treatment of mycobacterial diseases, including Mycobacterium tuberculosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.