Methods of generating natural killer cells

US8926964B2 · kind B2 · utility

Assignee

• Anthrogenesis Corporation · US

Inventors

• Robert J. Hariri · New York, US
• Mohammad Heidaran · Chatham, US
• Stephen Jasko · Rutherford, US
• Lin Kang · Beijing, CN
• Eric Law · Florham Park, US
• Ajai Pal · Bound Brook, US
• Bhavani STOUT · Lebanon, US
• Vanessa Voskinarian-Berse · Millington, US
• Andrew Zeitlin · Green Brook, US
• Xiaokui Zhang · Northborough, US

Key dates

• Filing date: Jul 13, 2011
• Grant date: Jan 6, 2015
• Expiry date: Jul 13, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are methods of producing natural killer cells using a two-step expansion and differentiation method. Also provided herein are methods of suppressing tumor cell proliferation, of treating individuals having cancer or a viral infection, comprising administering the NK cells produced by the method to an individual having the cancer or viral infection.