Compound sea cucumber product, preparation method, and dosage forms thereof

US8927008B2 · kind B2 · utility

Assignee

• Dalian Haiyantang Biology Co., Ltd. · CN

Inventors

• Jian Jiao · Tangxia, CN
• Junjie Shao · Dalian, CN

Key dates

• Filing date: Mar 3, 2011
• Grant date: Jan 6, 2015
• Expiry date: Mar 3, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2236/39
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound sea cucumber product, preparation method thereof and dosage forms thereof are disclosed. A fresh sea cucumber is cut open, the viscus thereof is taken out, and they are well-cleaned respectively and put into an airtight container; at 70˜130° C., gelatinate for 1 min˜20 hours; thereafter freeze-dry till the water content is less than 10 wt %; apply coarse crushing till the fineness reaches 10˜300 mesh; then apply ultra-micro crushing by means of an airflow crusher until the fineness reaches 100˜3000 mesh; lastly apply nanometer crushing by means of high-energy ball grinding mill till the fineness reaches 10˜1000 nm. The nanometer sea cucumber extract is mixed with panax pseudo-ginseng saponins extract at the proportion of 99˜80 wt %:1˜20 wt %. The compound preparation of nanometer sea cucumber and panax pseudo-ginseng saponins can greatly enhance the pharmacological functions of the sea cucumber single preparation or the panax pseudo-ginseng single preparation and eliminate the side effects of the single preparations when used alone. The compound preparation can achieve a better health-care effect than the single preparations and it can be applied for various health-care …