Compositions and methods for in vitro diagnostic tests including sulfonic acid
US8927226B2 · kind B2 · utility
0Cited by
6References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 30, 2014 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Apr 30, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/535
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides compositions, kits, and methods for performing colorimetric analysis. A substrate is reacted to generate a chromogenic reaction product, and a reaction stop reagent that is a sulfonic acid is added to stop and stabilize the reaction product. The absorbance properties of the chromogenic reaction product can be maintained over significantly longer periods of time of that of conventional reagents and methods. The sulfonic acid can be used in assays such as ELISAs in order to provide a more accurate and safer detection of analytes in a biological sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.