Methods for detecting dithio-containing proteins using quenched fluorophores conjugated to peptides via linkers containing dithio groups
US8927291B2 · kind B2 · utility
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Key dates
| Filing date | Oct 31, 2012 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Oct 31, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/182
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are dithio compounds that include a quenched fluorophore and a non-fluorophore peptide linked via a dithio bond to the fluorophore. The dithio compounds may be used in methods for detecting thiol-containing compounds or dithio-containing compounds. The dithio compounds also may be used as cellular probes where the peptide portion of the compounds targets the compounds to a specific cellular location.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.