Thio derivatives bearing lactams as potent HDAC inhibitors and their uses as medicaments
US8927533B2 · kind B2 · utility
1Cited by
1References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 17, 2012 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Sep 17, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel amide compounds of Formula (I), and their use as anti-tumoral and pro-apoptotic agents. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of HDAC is responsive, and the pharmaceutical composition containing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.