Therapeutic piperazines
US8927546B2 · kind B2 · utility
0Cited by
13References
10Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 22, 2010 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Feb 21, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention includes a compound of formula I:wherein R1, Y, A, n, R4 and Z have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of PDE4 function and are useful for improving cognitive function and/or treating cognitive disorders or impairment, traumatic and/or ischemic injuries of the central and peripheral nervous system and/or psychiatric disorders in animals, especially humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.