Patent · US Active

Crystalline pharmaceutical and methods of preparation and use thereof

US8927574B2 · kind B2 · utility

22Cited by
63References
9Claims
0Family size

Assignee

Inventor

Key dates

Filing dateDec 13, 2012
Grant dateJan 6, 2015
Priority date
Expiry dateJan 4, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.