Patent · US Active

Method for preventing the crystallisation of pharmaceuticals in a polymer film

US8932665B2 · kind B2 · utility

0Cited by

3References

18Claims

0Family size

Assignee

LTS Lohmann Therapie-Systeme AG · DE

Inventors

Johannes Josef Leonhard · Bendorf, DE
Walter Mueller · Andernach, DE

Key dates

Filing date	Oct 26, 2010
Grant date	Jan 13, 2015
Priority date	—
Expiry date	Oct 26, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/006
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a method for preventing the crystallization of a pharmaceutical in a polymer film, wherein the solvent-containing coating compound, which comprises a matrix-forming polymer or polymer mixture and at least one pharmaceutical and is spread to produce the polymer film, is temporarily dried at temperatures that is at least 10° C. above the melting temperature of the pharmaceutical contained in the coating compound. The maximum temperature is thus higher than that which is required for mere drying and obviates the need for an additional, time-consuming and expensive work step.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.