Process for the enantioselective enzymatic reduction of intermediates

US8932835B2 · kind B2 · utility

Assignee

• IEP GMBH · US

Inventors

• Antje Gupta · Wiesbaden, DE
• Maria Bobkova · Idstein, DE
• Anke Tschentscher · Eltville am Rhein, DE

Key dates

• Filing date: Sep 22, 2008
• Grant date: Jan 13, 2015
• Expiry date: Jul 21, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P7/04
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A process for the enantioselective enzymatic reduction of a keto compound of general formula Iwherein R may represent any protective group for amino functions (tert. butyloxycarbonyl group (BOC), benzyloxycarbonyl group, 9-fluorenylmethoxycarbonyl group) and X═—Cl, —CN, —OH, Br, F.