Macrocyclic compounds as Trk kinase inhibitors
US8933084B2 · kind B2 · utility
80Cited by
4References
52Claims
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Key dates
| Filing date | May 13, 2011 |
| Grant date | Jan 13, 2015 |
| Priority date | — |
| Expiry date | May 13, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.