Anti-obesity potential of Calebin A
US8933121B2 · kind B2 · utility
1Cited by
4References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 10, 2012 |
| Grant date | Jan 13, 2015 |
| Priority date | — |
| Expiry date | Jan 10, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses the potential of Calebin A in inhibiting adipogenesis and applications thereof in obesity management. The present invention elucidates the potential of Calebin A to favorably modulate biochemical markers associated with obesity. Notable biomodulatory properties of Calebin A include inhibiting leptin production, increasing adiponectin expression and inhibiting local (adipocyte) and systemic inflammation caused by pro-inflammatory cytokines Tumor Necrosis Factor (TNF-α), Interleukin-6 (IL-6) and Interleukin-1 (IL-1β).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.