Immunoenhancer-linked oligomeric HIV envelope peptides
US8936789B2 · kind B2 · utility
2Cited by
2References
15Claims
0Family size
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Key dates
| Filing date | Oct 16, 2009 |
| Grant date | Jan 20, 2015 |
| Priority date | — |
| Expiry date | Mar 22, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are immunogenic compositions comprising fusion proteins, the fusion proteins comprising lentivirus gp41 or a fragment thereof, a trimerization or oligomerization motif and an immunoenhancer that elicit potent and broad HIV neutralizing antibody responses in the immunized hosts. Also disclosed are methods of making and using the immunogenic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.