Patent · US Active

Substituted pyrrolo[2,3-B]pyrazine compounds and their use

US8937069B2 · kind B2 · utility

1Cited by
1References
9Claims
0Family size

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Key dates

Filing dateJan 11, 2013
Grant dateJan 20, 2015
Priority date—
Expiry dateJan 11, 2033

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (Ia) and (Ib) which activate the IP receptor, processes for preparing them, pharmaceutical compositions comprising said compounds and uses thereof. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various organs in animal models and in patients.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.