Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
US8937163B2 · kind B2 · utility
5Cited by
27References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 28, 2012 |
| Grant date | Jan 20, 2015 |
| Priority date | — |
| Expiry date | Mar 28, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel antibodies and antigen binding fragments that specifically bind to KAAG1 and which may be used in the treatment, detection and diagnosis of cancer comprising KAAG1-expressing cells are disclosed herein. Cells expressing the antibodies and antigen binding fragments as well as methods of detecting and treating cancer using the antibodies and fragments are also disclosed. Cancer indications which may benefit from such treatment or detection include ovarian cancer, renal cancer, lung cancer, colorectal cancer, breast cancer, brain cancer, and prostate cancer, as well as melanomas.
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