Nucleic-acid-responsive gel, method for producing same, and use of same
US8937171B2 · kind B2 · utility
0Cited by
3References
12Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 6, 2007 |
| Grant date | Jan 20, 2015 |
| Priority date | — |
| Expiry date | Feb 3, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a nucleic-acid-responsive gel which allows (i) a larger volumetric change through structural design, (ii) adjustment of its recognition ability to recognize a nucleic acid, (iii) improvement of sensitivity, and (iv) flexible design according to, e.g., a sequence of target DNA. The nucleic-acid-responsive gel includes a probe formed of two single-stranded nucleic acids which are hybridized with each other. The probe is fixed within a network structure of a polymer gel. The two single-stranded nucleic acids are bound reversibly with each other.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.