Patent · US Active

Process for the preparation of lasofoxifene tartrate

US8937188B2 · kind B2 · utility

0Cited by

3References

16Claims

0Family size

Assignee

Glenmark Generics Limited · IN

Inventors

Mubeen Ahmed Khan · Navi Mumbai, IN
Nikhil Trivedi · Navi Mumbai, IN
Nagan Nirmalan Kandasamy · Titwala, IN
Dayaghan Gangadhar Patil · Kalyan-Dombivli, IN
Vipin Kumar Pandey · Mirzapur, IN
Sukumar Sinha · Mumbai, IN

Key dates

Filing date	Apr 27, 2010
Grant date	Jan 20, 2015
Priority date	—
Expiry date	Sep 1, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2982
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A solid crystalline form of 1-(2-[4-(6-methoxy-3,4-dihydronaphthalene-1-y) phenoxy]ethyl)pyrrolidine, and a preparing process thereof are provided. The aforesaid compound is a key intermediate in the synthesis of lasofoxifene. A process for preparing lasofoxifene, a process for purifying lasofoxifene tartrate, and a crystalline form of lasofoxifene tartrate are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.