High-molecular weight conjugate of podophyllotoxins
US8940332B2 · kind B2 · utility
5Cited by
38References
5Claims
0Family size
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Key dates
| Filing date | May 16, 2007 |
| Grant date | Jan 27, 2015 |
| Priority date | — |
| Expiry date | May 26, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L2205/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel podophyllotoxin derivative, which is capable of releasing a drug without depending on biological enzymes and can be expected to have an effective therapeutic effect and is soluble in water has been demanded. A polymer having a polyethyleneglycol structural unit and two or more succinic monoamide structural units, particularly a polymer conjugate of a podophyllotoxin in which a carboxylic acid group of polyethyleneglycol/polyaspartic acid copolymer and a hydroxyl group of podophyllotoxin and linked via an ester bond is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.