Cancer diagnosis and treatment of cancer using anti-robo 1 antibody
US8940488B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 31, 2005 |
| Grant date | Jan 27, 2015 |
| Priority date | — |
| Expiry date | May 29, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/734
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.