Methods for ligation and uses thereof
US8940501B2 · kind B2 · utility
16Cited by
61References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 1, 2010 |
| Grant date | Jan 27, 2015 |
| Priority date | — |
| Expiry date | Jul 9, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2217/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods for ligation. The invention provides novel reagents and methods for ligating an acyl donor compound with an acyl acceptor compound. Provided acyl donor compounds comprise a transamidase recognition sequence that allows ligation with a nucleophilic acyl acceptor in the presence of transamidase. The invention further provides kits comprising acyl donor compounds and optionally comprising other reagents for ligation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.