Methods and compositions for enhancing delivery of double-stranded RNA or a double-stranded hybrid nucleic acid to regulate gene expression in mammalian cells
US8940857B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 30, 2010 |
| Grant date | Jan 27, 2015 |
| Priority date | — |
| Expiry date | Aug 30, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01023
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A delivery-enhancing peptide comprising the amino acid sequence of SEQ ID NO:11 or salt thereof. This invention is directed towards methods and compositions to administer a double-stranded ribonucleic acid to a mammal so as to effectuate transfection of the double-stranded RNA into a desired tissue of the mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.