Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds
US8940859B2 · kind B2 · utility
6Cited by
7References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2012 |
| Grant date | Jan 27, 2015 |
| Priority date | — |
| Expiry date | Nov 25, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/36
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.