Crystalline anti-human IL-12 antibodies

US8940873B2 · kind B2 · utility

Assignee

• Abb Vie Inc. · US

Inventors

• David W. Borhani · Worcester, US
• Wolfgang Fraunhofer · Gurnee, US
• Hans-Juergen Krause · Havelsee, DE
• Anette Koenigsdorfer · Ilvesheim, DE
• Gerhard Winter · Dossenheim, DE
• Stefan Gottschalk · Grünwald, DE

Key dates

• Filing date: Feb 7, 2013
• Grant date: Jan 27, 2015
• Expiry date: Feb 7, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to batch crystallization methods for crystallizing an anti-hIL-12 antibody that allows the production of the antibody on an industrial scale, antibody crystals obtained according to the methods, compositions containing the crystals, and methods of using the crystals and the compositions.