Patent · US Active

Aminothiazole compounds as kinase inhibitors and methods of using the same

US8940894B2 · kind B2 · utility

0Cited by
3References
3Claims
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Assignee

Inventors

Key dates

Filing dateMay 10, 2013
Grant dateJan 27, 2015
Priority date
Expiry dateMay 10, 2033

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula I:which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.