2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application

US8940900B2 · kind B2 · utility

Assignee

• Advinus Therapeutics Limited

Inventors

• Kasim Mookhtiar · Jamkhed, IN
• Debnath Bhuniya · Pune, IN
• Bhavesh Dave · Bengaluru, IN
• Gobind S. Kapkoti · Jamkhed, IN
• Sujay Basu · Mumbai, IN
• Anita Chugh · Delhi, IN
• Siddhartha De · Bengaluru, IN
• Venkata P. Palle · Mountain View, US

Key dates

• Filing date: Feb 25, 2008
• Grant date: Jan 27, 2015
• Expiry date: Mar 24, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the present disclosure are 2,2,2-tri-substituted acetamide derivatives of formula (I), its polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts and formulations thereof, useful as Glucokinase activator.