Biphasic lipid-vesicle compositions
US8945529B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2008 |
| Grant date | Feb 3, 2015 |
| Priority date | — |
| Expiry date | Oct 18, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biphasic lipid vesicle composition for treating cervical displasia by intravaginal delivery. The composition includes a suspension of lipid-bilayer vesicles having entrapped therein, an oil-in-water emulsion, human interferon alpha-2b and L-methionine, the composition having an interferon alpha-2b specific activity of between about 1-10 MIU (million international units) per gram composition, and between 0.01 to 0.5 weight percent L-methionine. In the treatment method, the composition is administered at a dose of between about 1-20 MIU interferon alpha-2b, and this dose is administered at least 3 days/week, for a period of at least 4 weeks.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.