Treatment of IgE-mediated disease
US8945575B2 · kind B2 · utility
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4References
24Claims
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Key dates
| Filing date | Dec 1, 2010 |
| Grant date | Feb 3, 2015 |
| Priority date | — |
| Expiry date | Dec 1, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The methods and compositions described herein are based, in part, on the discovery of a polypeptide of soluble CD23 (sCD23) that binds and sequesters IgE. Thus, the sCD23 peptides, polypeptides and derivatives described herein are useful for treating conditions or disorders involving increased IgE levels such as e.g., allergy, anaphylaxis, inflammation, lymphoma, and certain cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.