Thermosetting neutralized chitosan composition forming a hydrogel, lyophilizate, and processes for producing the same
US8945609B2 · kind B2 · utility
2Cited by
5References
12Claims
0Family size
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Key dates
| Filing date | Dec 23, 2005 |
| Grant date | Feb 3, 2015 |
| Priority date | — |
| Expiry date | Jan 29, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/003
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The aqueous thermosetting neutralized chitosan composition, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C., comprises 0.1 to 5.0 w/w %, based on the total composition, of a reacetylated chitosan having a molecular weight of not smaller than 100 kDa and a deacetylation degree of 40 to 70%, neutralized with an hydroxylated base, and 1 to 30 w/w %, based on the total composition, of a complexing agent selected from polyoses and polyols derived from polyoses. Said composition is useful for the preparation of an injectable formulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.