Ketol-acid reductoisomerase using NADH
US8945899B2 · kind B2 · utility
31Cited by
8References
6Claims
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Key dates
| Filing date | Dec 15, 2009 |
| Grant date | Feb 3, 2015 |
| Priority date | — |
| Expiry date | Oct 7, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for the evolution of NADPH specific ketol-acid reductoisomerase enzymes to acquire NADH specificity are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from Pseudomonas that have undergone co-factor switching to utilize NADH are described.
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