Patent · US Active

Devices, systems, and methods for conducting sandwich assays using sedimentation

US8945914B1 · kind B1 · utility

18Cited by
83References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 28, 2010
Grant dateFeb 3, 2015
Priority date
Expiry dateFeb 5, 2032

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2015/045
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Embodiments of the present invention are directed toward devices, systems, and method for conducting sandwich assays using sedimentation. In one example, a method includes generating complexes on a plurality of beads in a fluid sample, individual ones of the complexes comprising a capture agent, a target analyte, and a labeling agent. The plurality of beads including the complexes may be transported through a density media, wherein the density media has a density lower than a density of the beads and higher than a density of the fluid sample, and wherein the transporting occurs, at least in part, by sedimentation. Signal may be detected from the labeling agents of the complexes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.