Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols

US8946124B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Thomas Bretschneider · Lohmar, DE
• Reiner Fischer · Monheim, DE
• Stefan Lehr · Leverkusen, DE
• Elmar Gatzweiler · Bad Nauheim, DE
• Ulrich Görgens · Ratingen, DE
• Isolde Häuser-Hahn · Leverkusen, DE
• Ines Heinemann · Hofheim, DE
• Arnd Voerste

Key dates

• Filing date: Feb 14, 2012
• Grant date: Feb 3, 2015
• Expiry date: Feb 14, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/54
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel compounds of the formula (I)in which W, X, Y, Z, A, B, D and G have the meanings given above,to a plurality of processes and intermediates for their preparation, and to their use as pesticides and/or herbicides and/or fungicides.The invention also relates to selective herbicidal compositions comprising, firstly, the halogen-substituted spirocyclic ketoenols and, secondly, a crop plant compatibility-improving compound.The present invention furthermore relates to the boosting of the action of crop protection compositions comprising, in particular, halogen-substituted spirocyclic ketoenols, through the addition of ammonium salts or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for producing them and to their application in crop protection as pesticides and/or fungicides and/or for preventing unwanted plant growth.The invention also relates to substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones of the formula (Ia) for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumor disorders.