Processes for preparing 3-benzazepines

US8946207B2 · kind B2 · utility

Assignee

• Arena Pharmaceuticals, Inc. · US

Inventors

• Beverly L. Wolgast · San Diego, US
• Charles A. Gilson, III · San Diego, US
• Shelley Aytes · San Diego, US
• Scott A. Estrada · Village of La Jolla, US
• Dipanjan Sengupta · Goleta, US
• Brian Smith · San Diego, US
• Max Rey · Wallisellen, CH
• Ulrich Weigl · Hilzingen, DE

Key dates

• Filing date: Sep 14, 2012
• Grant date: Feb 3, 2015
• Expiry date: Sep 14, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C231/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides processes and intermediates for the preparation of 3-benzazepines and salts thereof which can be useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.