Patent · US Active

Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors

US8946259B2 · kind B2 · utility

1Cited by
1References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 28, 2013
Grant dateFeb 3, 2015
Priority date
Expiry dateOct 28, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to benzazole compounds that inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.