Patent · US Active

Methods for treating heart arrhythmia

US8948865B2 · kind B2 · utility

61Cited by

354References

20Claims

0Family size

Assignee

MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. · LU

Inventors

Denise Zarins · Los Gatos, US
Hanson S. Gifford, III · Woodside, US

Key dates

Filing date	Nov 15, 2013
Grant date	Feb 3, 2015
Priority date	—
Expiry date	Nov 15, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y304/24069
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods and apparatus are provided for treatment of heart arrhythmia via renal neuromodulation. Such neuromodulation may effectuate irreversible electroporation or electrofusion, ablation, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, such neuromodulation is achieved through application of an electric field. In some embodiments, such neuromodulation is achieved through application of neuromodulatory agents, of thermal energy and/or of high intensity focused ultrasound. In some embodiments, such neuromodulation is performed in a bilateral fashion.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.